Vaidehi Paranjape, Natalia Henao-Guerrero, Giulio Menciotti,  have published  "Performance of four cardiac output monitoring techniques vs. intermittent pulmonary artery thermodilution during a modified passive leg raise maneuver in isoflurane-anesthetized dogs" in Frontiers in Veterinary Science.

When animals are undergoing anesthesia, it's important to continuously monitor their fluid levels. If fluid levels suddenly drop, cardiac output can become harder to measure. In human medicine, a common way to predicts whether cardiac output will increase along with increased fluid volume during acute circulatory failure is passive leg raising (PLR), where the limbs are lifted to force blood toward the heart.

This study investigated the performance among four cardiac output (CO) monitoring techniques in comparison with the reference method intermittent pulmonary artery thermodilution (iPATD) and their ability to diagnose fluid responsiveness (FR) during a modified passive leg raise (PLRM) maneuver in isoflurane-anesthetized dogs undergoing acute blood volume manipulations. The study also examined the simultaneous effect of performing the PLRM on dynamic variables such as stroke distance variation (SDV), peak velocity variation (PVV), and stroke volume variation (SVV).

Paranjape is assistant professor of anesthesiology and pain management, Guerrero is service chief and associate professor of anesthesiology, and Menciotti is assistant professor of cardiology in the college's Department of Small Animal Clinical Sciences, which is led by department head Guerrero.