Current Studies
Owners and referring vets seeking to enroll an animal in a current study should carefully review the study description and enrollment criteria below.
Need more options?
The American Veterinary Medical Association Animal Health Studies Database lists hundreds of ongoing studies at sites throughout the U.S. and Canada.
Current clinical trials and translational research studies at VMCVM
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Noninvasive Treatment of Liver Tumors in DogsThis study plans to evaluate the effects of histotripsy, an ultrasound-based treatment that can non-invasively destroy tumor tissue without radiation or heat, on dogs with liver tumors.
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Diagnostic accuracy of heart murmurs in small breed dogsPurpose: To see how accurate a standard x-ray is for detecting a serious, early-stage heart condition in dogs. We will be looking at dogs who were found to have a heart murmur during a regular checkup but are not showing any outward signs of illness.
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Evaluating Effects of a new Bone Tumor TreatmentPurpose: To evaluate the effects of histotripsy, a novel treatment for that can destroy tissue without radiation or heat, on dogs with osteosarcoma.
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Amputation and Chemotherapy for OsteosarcomaWe are seeking dogs whose owners have decided on the standard of care treatment option for canine osteosarcoma. This includes amputation and chemotherapy. This study aims to check for the spread (metastasis) of the cancer and will follow patients until the time which the dog develops metastasis. We will use this information to compare against our other clinical trials.
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A Nerve Conduction study on Dogs with Intervertebral Disc ExtrusionPurpse: To determine if a nerve test, performed on paralyzed dogs before surgery for a slipped disc, can predict whether they will regain the ability to walk.
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Canine LipomasPurpose: To evaluate the safety and effectiveness of treating lipomas in dogs with a single treatment.
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The Role of Habitual Physical Activity on Pregnancy Health and Whelping in DogsPurpose: To identify how routine physical activity affected the health of the pregnancy and ease of whelping in dogs.
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Analyzing the hearts of Cavalier King Charles spaniel puppiesPurpose: To monitor the mitral valve structure of Cavalier King Charles Spaniel (CKCS) puppies and to compare the structure of CKCS puppies’ mitral valves to puppies of other breeds.
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Cavalier King Charles Spaniels and SleepPurpose: To understand the relationship between sleep and pain in Cavalier King Charles Spaniels and develop new methods to detect pain.
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Targeted chemotherapy for brain tumors in dogsPurpose: To determine the safety and effectiveness of a new chemotherapy drug and drug delivery method in the treatment of brain tumors (gliomas) in dogs.
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Use of new ultrasound technology to destroy tumor tissue in dogs with brain tumorsPurpose: To investigate the safety and antitumor activities of a new ultrasonic technology, called histotripsy, that can noninvasively destroy (ablate) tumor tissue using acoustic energy, in dogs with brain tumors.
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Evaluating an enzyme related to blood clotting disordersPurpose: To evaluate the role of ADAMTS13, an enzyme related to blood clotting, in dogs with presumptive idiopathic immune thrombocytopenia.
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Evaluating Blood Clotting Activity in Cats with Heart DiseasePurpose: To evaluate cats with hypertrophic cardiomyopathy (HCM) for abnormal blood clotting activity.
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Assessing Post Surgical Pain in PigsPurpose: To test if minimally-invasive ovary removal will have fewer complications and improve recovery in pet pigs compared to the traditional abdominal surgery ovariohysterectomy spay technique
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A new screening tool for dilated cardiomyopathy in Doberman PinschersPurpose: To test whether speckle tracking echocardiography will be able to detect changes in the hearts of Dobermans who have abnormal 24-hour Holter monitoring but normal standard echocardiograms.
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How Nutrition, Weight and Exercise affect Fertility and Reproduction in Female DogsPurpose: To identify how body condition, exercise, and nutrition affect the reproductive potential of female dogs and the health of their puppies.
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Assessing Blood Pressure Monitoring in Dogs Undergoing AnesthesiaPurpose: To test whether using advanced cardiac monitoring techniques provides a more accurate measurement of cardiac output and helps clinicians better determine when anesthetized dogs need more cardiovascular support to maintain a healthy cardiac output.
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A Survey on Whelping in The Female DogPurpose: To create a large database on the timing of whelping milestones in dogs.
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Identifying Molecules to Aid in Developing a Vaccine Against EPM (Equine Protozoal Myeloencephalitis)Purpose: To identify immune molecules that may be protective against S. neurona infection as a first step towards developing a vaccine against EPM.
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Evaluating the Hearts of Young Cavalier King Charles SpanielsPurpose: To evaluate if young CKCSs with mild mitral regurgitation develop heart enlargement earlier than young CKCSs with no mitral regurgitation.
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3-D Evaluation of the Feline HeartPurpose: To assess the feasibility of performing 3D echocardiography in healthy cats and to establish the standard range of dimensions for measuring the heart chambers in healthy cats
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A Non-Invasive Approach to treating Equine SarcoidsPurpose: To evaluate the effectiveness of histotripsy as a non-invasive therapeutic approach for treating equine sarcoids.
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New Testing to Predict Survival Times in Sick CatsThis study will test feline Thyroid Stimulating Hormone (fTSH) using a new method on ill and healthy cats to determine if this test can predict outcomes and guide clinical decisions.
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A Survey on Parasite Control PracticesThe aim of this study is to evaluate the parasite control practices implemented by dog owners for their pets. Additionally, we will assess dog owners' awareness and knowledge regarding parasite prevention and management.