Current Studies

Owners and referring vets seeking to enroll an animal in a current study should carefully review the study description and enrollment criteria below.
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The American Veterinary Medical Association Animal Health Studies Database lists hundreds of ongoing studies at sites throughout the U.S. and Canada.
Current clinical trials and translational research studies at VMCVM
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General ItemAnalyzing the hearts of Cavalier King Charles spaniel puppies
Purpose: To monitor the mitral valve structure of Cavalier King Charles Spaniel (CKCS) puppies and to compare the structure of CKCS puppies’ mitral valves to puppies of other breeds.
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General ItemCavalier King Charles Spaniels and Sleep
Purpose: To understand the relationship between sleep and pain in Cavalier King Charles Spaniels and develop new methods to detect pain.
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General ItemTargeted chemotherapy for brain tumors in dogs
Purpose: To determine the safety and effectiveness of a new chemotherapy drug and drug delivery method in the treatment of brain tumors (gliomas) in dogs.
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General ItemUse of new ultrasound technology to destroy tumor tissue in dogs with brain tumors
Purpose: To investigate the safety and antitumor activities of a new ultrasonic technology, called histotripsy, that can noninvasively destroy (ablate) tumor tissue using acoustic energy, in dogs with brain tumors.
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General ItemEvaluating an enzyme related to blood clotting disorders
Purpose: To evaluate the role of ADAMTS13, an enzyme related to blood clotting, in dogs with presumptive idiopathic immune thrombocytopenia.
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General ItemEvaluating Blood Clotting Activity in Cats with Heart Disease
Purpose: To evaluate cats with hypertrophic cardiomyopathy (HCM) for abnormal blood clotting activity.
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General ItemAssessing Post Surgical Pain in Pigs
Purpose: To test if minimally-invasive ovary removal will have fewer complications and improve recovery in pet pigs compared to the traditional abdominal surgery ovariohysterectomy spay technique
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General ItemEvaluating Effects of a new Bone Tumor Treatment
Purpose: To evaluate the effects of histotripsy, a novel treatment for that can destroy tissue without radiation or heat, on dogs with osteosarcoma.
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General ItemA new screening tool for dilated cardiomyopathy in Doberman Pinschers
Purpose: To test whether speckle tracking echocardiography will be able to detect changes in the hearts of Dobermans who have abnormal 24-hour Holter monitoring but normal standard echocardiograms.
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General ItemHow Nutrition, Weight and Exercise affect Fertility and Reproduction in Female Dogs
Purpose: To identify how body condition, exercise, and nutrition affect the reproductive potential of female dogs and the health of their puppies.
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General ItemAssessing Blood Pressure Monitoring in Dogs Undergoing Anesthesia
Purpose: To test whether using advanced cardiac monitoring techniques provides a more accurate measurement of cardiac output and helps clinicians better determine when anesthetized dogs need more cardiovascular support to maintain a healthy cardiac output.
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General ItemA Survey on Birthing and The Female Dog
Purpose: To create a large database on the timing of whelping milestones in dogs.
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General ItemIdentifying Molecules to Aid in Developing a Vaccine Against EPM (Equine Protozoal Myeloencephalitis)
Purpose: To identify immune molecules that may be protective against S. neurona infection as a first step towards developing a vaccine against EPM.
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General ItemEvaluating the Hearts of Young Cavalier King Charles Spaniels
Purpose: To evaluate if young CKCSs with mild mitral regurgitation develop heart enlargement earlier than young CKCSs with no mitral regurgitation.
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General Item3-D Evaluation of the Feline Heart
Purpose: To assess the feasibility of performing 3D echocardiography in healthy cats and to establish the standard range of dimensions for measuring the heart chambers in healthy cats
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General ItemA Non-Invasive Approach to treating Equine Sarcoids
Purpose: To evaluate the effectiveness of histotripsy as a non-invasive therapeutic approach for treating equine sarcoids.
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General ItemNew Testing to Predict Survival Times in Sick Cats
This study will test feline Thyroid Stimulating Hormone (fTSH) using a new method on ill and healthy cats to determine if this test can predict outcomes and guide clinical decisions.
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General ItemA Survey on Parasite Control Practices
The aim of this study is to evaluate the parasite control practices implemented by dog owners for their pets. Additionally, we will assess dog owners' awareness and knowledge regarding parasite prevention and management.