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Virginia-Maryland College of Veterinary Medicine has a robust research program that spans basic biomedical sciences in infectious (viral, bacterial, and parasitic) and non-infectious (immune-mediated and oncologic) diseases to veterinary clinical research to translational to public health. The program's overall goal is to apply our research to improve the lives of pets and people.
Basic biomedical sciences include the use of appropriate animal models for diseases to better understand the disease process, a prerequisite for the development of better preventive and therapeutic strategies.
With a focus on One Health, our program brings together veterinarians, physicians, and other scientists to address public health threats affecting both people and animals.
Our translational research approach aims to take laboratory findings directly to clients in a clinical setting.
Ongoing clinical trials in our hospitals test research discoveries to develop better methods of disease prevention, diagnosis, and treatment.
Our faculty, students, staff, and research partners are committed to discovery, service, and training future researchers and veterinarians.
Centers
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Article ItemCenter for One Health Research , article
The Center for One Health Research (COHR) gathers faculty, staff, and students from VA-MD Vet Med and the Edward Via College of Osteopathic Medicine who have a shared interest in cooperative research and scholarship related to infectious diseases. This collaboration is founded on the two schools’ One Health philosophy, which is based on the understanding that animal health, human health, and the environment are inextricably linked; consequently, professionals from these fields must work together to protect, promote, and improve overall health. The center coordinates research, instruction, and outreach activities related to understanding the disease processes that affect both animal and human health, and supports the continued advancement of the science and technology of disease-intervention strategies.
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Article Item(Meta)Genomics-Based Pathogen Identification Center for Animal and Plant Disease Diagnostics, Biosecurity, and Pandemic Prevention , article
Today’s growing destruction of ecosystems, worldwide trade of plant and animals, and human travel exasperate the risk of plant and animal disease emergence and spread. Early detection, precise identification, and thorough characterization of emerging pathogens using agnostic genomic and metagenomic sequencing could lead to faster interventions to lower the chances that a local disease outbreak turns into an epidemic or pandemic. Therefore, at Virginia Tech, the Virginia Tech Animal Laboratory Services and the Virginia Tech Plant Disease Clinic joined forces to establish a (meta)genomics-based pathogen identification service center for animal and plant disease diagnostics, biosecurity, and pandemic prevention.
Signature Research Programs
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Article ItemComparative, Translational, and Veterinary Research , article
Research themes include clinical veterinary medicine research and translational medicine from laboratory animals to clinical veterinary and human patients; stem cell biology and its application; clinical trials management; and human-animal bond/interactions.
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Article ItemImmune-mediated / Inflammatory Diseases Research , article
Research themes include animal models for immune-mediated diseases, and understanding the mechanisms of such as autoimmune diseases and inflammatory diseases (eg. inflammatory bowel disease). Specific interests include role of epigenetics, microbiome, and environmental hormonal factors on these diseases; transition of inflammation leading to cancer; induction of immunity in oncologic conditions; and translational research.
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Article ItemNeuropathobiology Research , article
Research themes include animal models for neurodevelopment and traumatic injury, neurovascularization, neuroinflammation, and neuro-oncology; and translational research.
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Article ItemPathogenic Microbiology / Infectious Diseases Research , article
Research themes include animal models for human and veterinary infectious diseases; and understanding the pathogenesis of the diseases, immunity to infectious and its prevention: development of vaccines and drugs, mechanisms of drug resistance, and translational research.
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Article ItemPublic Health Research , article
Research focused on infectious diseases epidemiology and public health education that addresses the individual, social, and ecological determinants of health, reflects the human-animal-environment One Health interface, promotes health equity, and builds healthy communities.
Laboratories
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Research Training Programs
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Latest News
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Article ItemVirginia Tech student explores promising treatment avenue for lupus , article
With support from a new National Institutes of Health Ruth L. Kirschstein National Research Service Award F30 award, Oakland is exploring an approach that uses DNA-like molecules that imitate bacterial DNA and have the potential to possibly ease lupus symptoms.
Date: Dec 17, 2024 -
Article ItemNew Virginia Tech cancer researcher seeks to understand and predict deadly tumor metastasis , article
Shenglin Mei, the newest principal investigator of the Fralin Biomedical Research Institute at VTC’s growing Cancer Research Center in Washington, D.C., applies computational biology, genetics, and immunology to study cancer’s spread away from the primary tumor.
Date: Dec 17, 2024 -
Article ItemStudy assesses virulence of Cryptococcus strains, laying groundwork for improved treatment , article
The laboratory of Kirsten Nielsen in the Center for One Health Research has completed a six-year study to examine the virulence of 38 clinical isolates from various strains of Cryptococcus.
Date: Dec 09, 2024 -
Article ItemKatie LaVallee to lead Animal Resources and Care Division , article
Effective Dec. 1, LaVallee is responsible for overseeing the care and use of animals used in research, testing, and teaching across Virginia Tech.
Date: Nov 27, 2024 -
Article ItemResearch achievements and excellence honored during annual celebration , article
More than 80 Virginia Tech faculty members were honored during the Celebrating Scholarly Distinction ceremony.
Date: Nov 13, 2024 -
Article ItemInaugural recipients named for Lutz Awards , article
Sophia Economou, Zheng “Phil” Xiang, John Rossmeisl, and Markus Breitschmid earned the first Jacob A. Lutz III Awards for Eminent Scholars during Virginia Tech’s annual research awards ceremony, Celebrating Scholarly Excellence, on Nov. 6.
Date: Nov 12, 2024 -
Article ItemQ&A: Researchers focus on innovative treatments for brain tumors in dogs , article
November is National Pet Cancer Awareness Month. With over 6 million pets diagnosed with cancer every year, Virginia Tech’s work in pet cancer research represents a critical step toward more humane and effective care.
Date: Nov 11, 2024 -
Video ItemVirginia Tech researcher studies commonalities of canine and human brain cancer , video
John Rossmeisl Jr., the Dr. and Mrs. Dorsey Taylor Mahin Professor of Neurology and Neurosurgery at the Virginia-Maryland College of Veterinary Medicine at Virginia Tech, studies the commonalities between canine and human cancers — a connection that has major implications for treating intractable tumors. He is one the first four recipients of the Jacob A. Lutz III Award for Eminent Scholars for his innovative cancer research.
Date: Nov 08, 2024