Vaidehi Paranjape, Natalia Henao-Guerrero, Giulio Menciotti, All SACS and Siddharth Saksena VT Dept of Civil and Enviro Engineering have published  "Agreement between Electrical Cardiometry and Pulmonary Artery Thermodilution for Measuring Cardiac Output in Isoflurane-Anesthetized Dogs" in Animals.

Using general anesthesia on animals causes significant changes to the heart and blood vessels that disrupt normal cardiovascular performance. Blood pressure (BP) is used for closely monitoring hemodynamics in anesthetized animals. However, BP is affected by various factors and may not always accurately correlate with the total body blood flow. Pulmonary artery thermodilution (PATD) is the gold standard for cardiac output (CO) measurements, but, due to the high risks associated with its invasiveness, it is not performed in clinical settings. This study evaluates noninvasive electrical cardiometry’s (EC) performance in measuring CO and other hemodynamic variables in healthy anesthetized dogs during acute blood volume manipulation. The EC measurements consistently underpredict the CO values as compared with PATD, but have a better performance when acute blood loss occurs. Even though the EC readings have a slightly higher error than the accepted error, this method is very good at showing trends in the CO measured using PATD. Other EC-derived variables are able to closely track the changes in the CO measured using PATD. In clinics, noninvasive EC may benefit the patient care quality for anesthetized dogs by monitoring the trends in hemodynamics and guiding anesthetists to diagnose and treat cardiovascular complications.

Paranjape is assistant professor of anesthesiology and pain management, Guerrero is service chief and associate professor of anesthesiology, and Menciotti is assistant professor of cardiology in the college's Department of Small Animal Clinical Sciences, which is led by department head Guerrero.